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Transplant Proc ; 53(4): 1118-1125, 2021 May.
Article in English | MEDLINE | ID: covidwho-978450

ABSTRACT

INTRODUCTION: Living-donor liver transplantation (LDLT) has been mostly suspended and deceased-donor living transplantation activity has been considerably reduced because of coronavirus disease 2019 (COVID-19). We modified our protocols and procedures in line with COVID-19 guidelines. Since the restructuring, we have performed 20 LDLTs. Our study reports the outcomes of these cases and demonstrates the feasibility of LDLT during this pandemic. MATERIALS AND METHODS: The changes were influenced by experiences and communications from across the globe. A month-long self-imposed moratorium was spent in restructuring the program and implementing new protocols. Twenty LDLTs were performed between April 18 and September 15 using the new protocols. Our experience includes 2 simultaneous liver-kidney transplants, 1 ABO-incompatible LDLT, and 1 pediatric case (age 11 months). RESULTS: Nineteen patients recovered and 1 patient died. We maintained our postoperative immunosuppression protocol without many changes. Major complications were observed in 30% of recipients but none of the donors. One recipient was infected with COVID-19 during the postoperative period. A donor-recipient couple contracted COVID-19 after discharge from the hospital. All patients recovered from COVID-19 and liver enzymes were unaffected. CONCLUSION: This study represents a microcosm of experience in LDLT during the COVID-19 era. Outcomes of LDLT are not affected by COVID-19 per se, provided that we make necessary changes.


Subject(s)
COVID-19/prevention & control , Infection Control/methods , Liver Transplantation/methods , Postoperative Complications/prevention & control , SARS-CoV-2 , ABO Blood-Group System , Adult , Blood Group Incompatibility , COVID-19/immunology , COVID-19/virology , Female , Humans , Immunosuppression Therapy/methods , Infant , Liver Transplantation/adverse effects , Liver Transplantation/standards , Living Donors , Male , Middle Aged , Postoperative Complications/immunology , Postoperative Complications/virology , Postoperative Period , Treatment Outcome
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